Methoxyamine attack on cytosine produces ambivalent base pairing properties of the modified base.
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چکیده
منابع مشابه
A New Base-Modified Deoxycytidine Capable of Base Pairing With Guanine Using Four Hydrogen Bonds
Content Synthetic scheme of phosphoramidite 9b ------------------------------------------------------------------S3 Figure S1 ------------------------------------------------------------------------------------------------------S4 Figure S2 ------------------------------------------------------------------------------------------------------S4 Figure S3 -----------------------------------------...
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The chemical synthesis of ribonucleic acids (RNA) with novel chemical modifications is largely driven by the motivation to identify eligible functional probes for the various applications in life sciences. To this end, we have a strong focus on the development of novel fluorinated RNA derivatives that are powerful in NMR spectroscopic analysis of RNA folding and RNA ligand interactions. Here, w...
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...................................................................................................................... 334 Autobiographical Statement ........................................................................................ 338
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An understanding of why adenine (A) pairs with thymine (T) and cytosine (C) with guanine (G) in DNA is very useful in the design of sensors and other related devices. We report the use of dissociation energies, geometries and molecular electrostatic potentials (MEPs) to justify the canonical (AT and CG) Watson-Crick pairs. We also analyze all mismatches in both configurations-cis and trans-with...
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ژورنال
عنوان ژورنال: Acta Biochimica Polonica
سال: 1996
ISSN: 1734-154X,0001-527X
DOI: 10.18388/abp.1996_4568